Full-time Posted June 08, 2026
Apply Now

Job Description

Company Description

Bicycle Therapeutics is a clinical‑stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. The company is evaluating nuzafatide pevedotin (formerly 5528), a Bicycle® Drug Conjugate (BDC®) targeting EphA2, a historically undruggable target; zelenectide pevedotin (formerly BT8009), a BDC targeting Nectin-4, a well‑validated tumor antigen; and BT7480, a Bicycle Tumor‑Targeted Immune Cell Agonist® (Bicycle TICA®) targeting Nectin-4 and agonizing CD137, in company‑sponsored clinical trials. Additionally, the company is developing Bicycle® Radioconjugate...

Apply for This Position

Ready to take the next step? Click the button below to submit your application.

Submit Application